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Pancreatic Cancer News From Medical News Today
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Pancreatic Cancer May Be Identified By Molecular Marker From Pancreatic 'Juices'
Researchers at Mayo Clinic have developed a promising method to distinguish between pancreatic cancer and chronic pancreatitis - two disorders that are difficult to tell apart. A molecular marker obtained from pancreatic "juices" can identify almost all cases of pancreatic cancer, their study shows. The findings were being presented at...
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Among Patients Carrying BRCA Mutations, PARP Inhibitor Shows Activity In Pancreatic, Prostate Cancers
In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers...
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In Pancreatic Cancer, Breakthrough In The Understanding Of How The Cancer Cells Ingest Nutrients Points To New Drug Target
In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a notoriously lethal disease with few treatment options. Pancreatic cancer kills nearly 38,000 Americans annually, making it...
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Metastatic Pancreatic Cancer Targeted By Radioisotopes Attached To Listeria
Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them...
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Evidence-Based Overview For Physicians: Diagnosis And Management Of Pancreatic Cancer
Pancreatic cancer is the fourth leading cause of death from cancer, and while family physicians in Canada only see 1 case a year, the number of cases is expected to increase as the population ages. A review in CMAJ (Canadian Medical Association Journal) provides an evidence-based overview of diagnosis and...
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Hope For New Tailor-Made Anti-Cancer Agents
Scientists at the Walter and Eliza Hall Institute and their collaborators have tailor-made a new chemical compound that blocks a protein that has been linked to poor responses to treatment in cancer patients. The development of the compound, called WEHI-539, is an important step towards the design of a potential...
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Promising Phase I Clinical Trial Of Rogosertib Leads To Multi-Institutional Phase II Trial
Results of a phase 1 clinical trial reported at the American Association for Cancer Research (AACR) annual conference show that orally administered Rigosertib is well tolerated in patients with advanced solid tumors. This is the first trial in which orally administered Rigosertib, a dual kinase inhibitor, was studied in solid...
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New 2-Drug Combination Effective For Some Patients With Incurable Tumors And BRCA Mutations
A novel combination of two drugs has shown anti-cancer activity in patients who had incurable solid tumors and carried a germline mutation in their BRCA genes, Dana-Farber Cancer Institute researchers reported at the American Association for Cancer Research annual meeting in Washington, April 6-10...
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One Specific MicroRNA Appears To Promote Tumor Growth And Cancer Spread
Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in tumors, tumor inflammation, and metastasis. As a therapeutic target, miR-155 could potentially provide a new avenue of...
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Early Pancreatic Cancer Detection May Be Possible With New Metabolite-Based Diagnostic Test
A new diagnostic test that uses a scientific technique known as metabolomic analysis may be a safe and easy screening method that could improve the prognosis of patients with pancreatic cancer through earlier detection...
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